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Blockade of Electron Transport During Ischemia Preserves bcl-2 and Inhibits Opening of the Mitochondrial Permeability Transition Pore

Myocardial ischemia damages the electron transport chain and augments cardiomyocyte death during reperfusion. To understand the relationship between ischemic mitochondrial damage and mitochondrial-driven cell death, the isolated perfused heart underwent global stop-flow ischemia with and without mit...

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Autors principals: Chen, Qun, Lesnefsky, Edward J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076511/
https://ncbi.nlm.nih.gov/pubmed/21354418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2011.02.029
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