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The antiapoptotic gene survivin is highly expressed in human chondrosarcoma and promotes drug resistance in chondrosarcoma cells in vitro

BACKGROUND: Chondrosarcoma is virtually resistant to chemotherapy and radiation therapy. Survivin, the smallest member of the inhibitor of apoptosis protein family, is a critical factor for tumor progression and resistance to conventional therapeutic approaches in a wide range of malignancies. Howev...

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Detalhes bibliográficos
Main Authors: Lechler, Philipp, Renkawitz, Tobias, Campean, Valentina, Balakrishnan, Sanjeevi, Tingart, Markus, Grifka, Joachim, Schaumburger, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076263/
https://ncbi.nlm.nih.gov/pubmed/21457573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-120
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