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Effects of 17β-estradiol, and its metabolite, 4-hydroxyestradiol on fertilization, embryo development and oxidative DNA damage in sand dollar (Dendraster excentricus) sperm

Oxidative compounds have been demonstrated to decrease the fertilization capability and viability of offspring of treated spermatozoa. As estrogen and its hydroxylated metabolites readily undergo redox cycling, this study was undertaken to determine if estrogens and other oxidants could damage DNA a...

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Autori principali: Rempel, Mary Ann, Hester, Brian, DeHaro, Hector, Hong, Haizheng, Wang, Yinsheng, Schlenk, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076192/
https://ncbi.nlm.nih.gov/pubmed/19171371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scitotenv.2008.12.054
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