A Genome-wide Association Study Identifies a Locus on Chromosome 14q21 as a Predictor of Leukocyte Telomere Length and as a Marker of Susceptibility for Bladder Cancer

Telomeres play a critical role in maintaining genome integrity. Telomere shortening is associated with the risk of many aging-related diseases. Classic twin studies have shown that genetic components may contribute up to 80% of the heritability of telomere length. In the study we report here, we use...

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Detalhes bibliográficos
Main Authors: Gu, Jian, Chen, Meng, Shete, Sanjay, Amos, Christopher I., Kamat, Ashish, Ye, Yuanqing, Lin, Jie, Dinney, Colin P., Wu, Xifeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076128/
https://ncbi.nlm.nih.gov/pubmed/21460395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0063
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