Maintenance Treatment of Depression in Old Age: A Randomized, Double-blind, Placebo-Controlled Evaluation of the Efficacy and Safety of Donepezil Combined with Antidepressant Pharmacotherapy

CONTEXT: Cognitive impairment in late-life depression is a core feature of the illness. OBJECTIVE: to test whether donepezil + antidepressant is superior to placebo + antidepressant in (1) improving cognitive performance and instrumental activities of daily living and (2) reducing recurrences of dep...

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Main Authors: Reynolds, Charles F., Butters, Meryl A., Lopez, Oscar, Pollock, Bruce G., Dew, Mary Amanda, Mulsant, Benoit H., Lenze, Eric J., Holm, Margo, Rogers, Joan C., Mazumdar, Sati, Houck, Patricia R., Begley, Amy, Anderson, Stewart, Karp, Jordan F., Miller, Mark D., Whyte, Ellen M., Stack, Jacqueline, Gildengers, Ariel, Szanto, Katalin, Bensasi, Salem, Kaufer, Daniel I., Kamboh, M. Ilyas, DeKosky, Steven T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076045/
https://ncbi.nlm.nih.gov/pubmed/21199965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2010.184
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