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A discrete water exit pathway in the membrane protein cytochrome c oxidase

By using the non-redox-active Mg(2+)/Mn(2+) site of cytochrome c oxidase as a probe, water access from the outside of the enzyme and water escape from the buried active site were studied. Water movement was time-resolved by monitoring the magnetic interaction of the oxygen isotope (17)O with the Mn(...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Schmidt, Bryan, McCracken, John, Ferguson-Miller, Shelagh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307603/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2633243100
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