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C-Terminus of Clostridium perfringens Enterotoxin Downregulates CLDN4 and Sensitizes Ovarian Cancer Cells to Taxol and Carboplatin

PURPOSE: We have previously demonstrated that CLDN4 (encoding claudin-4), a cell tight junction (TJ) protein, is highly expressed in human epithelial ovarian cancers (EOC) but undetectable in normal ovaries. CLDN4 has been identified as a specific receptor for c-terminus of Clostridium perfringens e...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Gao, Zhijian, Xu, Xiaoyin, McClane, Bruce, Zeng, Qing, Litkouhi, Babak, Welch, William R., Berkowitz, Ross S., Mok, Samuel C., Garner, Elizabeth I.O.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075966/
https://ncbi.nlm.nih.gov/pubmed/21123456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1644
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