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Chromatin Remodeling During Mouse and Human Embryonic Stem Cell Differentiation

Embryonic stem cell (ESC) differentiation is an excellent model to study chromatin changes at developmentally regulated loci. Differentiating mouse and human ESCs increase genome-wide acetylation (euchromatic) and tri-methylation (heterochromatic) of lysine 9 on histone H3. The Oct4 locus is euchrom...

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Detalhes bibliográficos
Main Authors: Golob, Jonathan L, Paige, Sharon L, Muskheli, Veronica, Pabon, Lil, Murry, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075915/
https://ncbi.nlm.nih.gov/pubmed/18425849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21545
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