Preparation, characterization and targeting of micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles to cancer cells

BACKGROUND: The purpose of this study was to develop a method for targeted delivery of 10-hydroxycamptothecin (HCPT)-loaded nanoparticles (NPs) to cancer cells. METHODS: We first used a supercritical antisolvent process to prepare micronized HCPT (nHCPT), and then folate-conjugated human serum album...

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Detalhes bibliográficos
Main Authors: Li, Qingyong, Liu, Chen, Zhao, Xiuhua, Zu, Yuangang, Wang, Ying, Zhang, Baoyou, Zhao, Dongmei, Zhao, Qi, Su, Lin, Gao, Yang, Sun, Baihe
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075905/
https://ncbi.nlm.nih.gov/pubmed/21499429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S16144
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