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Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model

The treatment of brain disorders is one of the greatest challenges in drug delivery because of a variety of main barriers in effective drug transport and maintaining therapeutic concentrations in the brain for a prolonged period. The objective of this study was delivery of valproic acid (VPA) to the...

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Hlavní autoři: Eskandari, Sharareh, Varshosaz, Jaleh, Minaiyan, Mohsen, Tabbakhian, Majid
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075902/
https://ncbi.nlm.nih.gov/pubmed/21499426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S15881
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