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An efficient proteomics method to identify the cellular targets of protein kinase inhibitors

Small molecule inhibitors of protein kinases are widely used in signal transduction research and are emerging as a major class of drugs. Although interpretation of biological results obtained with these reagents critically depends on their selectivity, efficient methods for proteome-wide assessment...

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Autors principals: Godl, Klaus, Wissing, Josef, Kurtenbach, Alexander, Habenberger, Peter, Blencke, Stephanie, Gutbrod, Heidrun, Salassidis, Kostadinos, Stein-Gerlach, Matthias, Missio, Andrea, Cotten, Matt, Daub, Henrik
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC307585/
https://ncbi.nlm.nih.gov/pubmed/14668439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535024100
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