Divergent tRNA-like element supports initiation, elongation, and termination of protein biosynthesis

The cricket paralysis virus internal ribosome entry site (IRES) can, in the absence of canonical initiation factors and initiator tRNA (Met-tRNA(i)), occupy the ribosomal P-site and assemble 80S ribosomes. Here we show that the IRES assembles mRNA-80S ribosome complexes by recruitment of 60S subunit...

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Bibliographic Details
Main Authors: Jan, Eric, Kinzy, Terri Goss, Sarnow, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC307581/
https://ncbi.nlm.nih.gov/pubmed/14673072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2535183100
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