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Selective Control of Oligosaccharide Transfer Efficiency for the N-Glycosylation Sequon by a Point Mutation in Oligosaccharyltransferase

Asn-linked glycosylation is the most ubiquitous posttranslational protein modification in eukaryotes and archaea, and in some eubacteria. Oligosaccharyltransferase (OST) catalyzes the transfer of preassembled oligosaccharides on lipid carriers onto asparagine residues in polypeptide chains. Ineffici...

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Bibliographic Details
Main Authors: Igura, Mayumi, Kohda, Daisuke
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075672/
https://ncbi.nlm.nih.gov/pubmed/21357684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.213900
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