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Lack of Tyrosylprotein Sulfotransferase-2 Activity Results in Altered Sperm-Egg Interactions and Loss of ADAM3 and ADAM6 in Epididymal Sperm

Tyrosine O-sulfation is a post-translational modification catalyzed by two tyrosylprotein sulfotransferases (TPST-1 and TPST-2) in the trans-Golgi network. Tpst2-deficient mice have male infertility, sperm motility defects, and possible abnormalities in sperm-egg membrane interactions. Studies here...

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Detalhes bibliográficos
Main Authors: Marcello, Matthew R., Jia, Weitao, Leary, Julie A., Moore, Kevin L., Evans, Janice P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075652/
https://ncbi.nlm.nih.gov/pubmed/21339297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175463
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