The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

Mitochondrial cytochrome c oxidase plays an essential role in aerobic cellular respiration, reducing dioxygen to water in a process coupled with the pumping of protons across the mitochondrial inner membrane. An aspartate residue, Asp-51, located near the enzyme surface, undergoes a redox-coupled x-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tsukihara, Tomitake, Shimokata, Kunitoshi, Katayama, Yukie, Shimada, Hideo, Muramoto, Kazumasa, Aoyama, Hiroshi, Mochizuki, Masao, Shinzawa-Itoh, Kyoko, Yamashita, Eiki, Yao, Min, Ishimura, Yuzuru, Yoshikawa, Shinya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673090/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2635097100
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