The Function of Vascular Smooth Muscle Phosphodiesterase III is Preserved in Healthy Human Aging

Phosphodiesterase (PDE) III is an enzyme in vascular smooth muscle that metabolizes cyclic adenosine monophosphate (cAMP). Milrinone inhibits PDE III, increasing the availability of cAMP. Cyclic guanosine monophosphate (cGMP), which is regulated by nitric oxide (NO), also inhibits PDE III. The endot...

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Detalhes bibliográficos
Main Authors: Elvebak, Rachel L., Eisenach, John H., Joyner, Michael J., Nicholson, Wayne T.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075602/
https://ncbi.nlm.nih.gov/pubmed/21500398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2010.00232.x
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