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Chromatin structure predicts epigenetic therapy responsiveness in sarcoma
To formally explore the potential therapeutic effect of histone deacetylase inhibitors (HDACIs) and DNA-methyltransferase inhibitors (DNA-MIs) on sarcomas, we treated a large sarcoma cell line panel with five different HDACIs in the absence and presence of the DNA-MI decitabine. We observed that the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075587/ https://ncbi.nlm.nih.gov/pubmed/21216937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0724 |
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