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The functional plasticity of T cell subsets

In 1986, Robert Coffman and Timothy Mossman first described the division of CD4(+) T cells into functional subsets, termed T helper 1 (T(H)1) and T(H)2, based on cytokine production, and in doing so unwittingly opened a Pandora’s box of complexity and controversy. Although the mechanisms that regula...

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Autores principales: Bluestone, Jeffrey A., Mackay, Charles R., O’Shea, John J., Stockinger, Brigitta
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075537/
https://ncbi.nlm.nih.gov/pubmed/19809471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2654
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