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The functional plasticity of T cell subsets
In 1986, Robert Coffman and Timothy Mossman first described the division of CD4(+) T cells into functional subsets, termed T helper 1 (T(H)1) and T(H)2, based on cytokine production, and in doing so unwittingly opened a Pandora’s box of complexity and controversy. Although the mechanisms that regula...
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Autores principales: | , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075537/ https://ncbi.nlm.nih.gov/pubmed/19809471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2654 |
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