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Mechanism of Human Dermal Fibroblast Migration Driven by Type I Collagen and Platelet-derived Growth Factor-BB

Migration of human dermal fibroblasts (HDFs) is critical for skin wound healing. The mechanism remains unclear. We report here that platelet-derived growth factor-BB (PDGF-BB) is the major promotility factor in human serum for HDF motility on type I collagen. PDGF-BB recapitulates the full promotili...

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Detalhes bibliográficos
Main Authors: Li, Wei, Fan, Jianhua, Chen, Mei, Guan, Shengxi, Sawcer, David, Bokoch, Gary M., Woodley, David T.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307548/
https://ncbi.nlm.nih.gov/pubmed/14595114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0352
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