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Early Response to ErbB2 Over-Expression in Polarized Caco-2 Cells Involves Partial Segregation From ErbB3 by Relocalization to the Apical Surface and Initiation of Survival Signaling
In several human cancers, ErbB2 over-expression facilitates the formation of constitutively active homodimers resistant to internalization which results in progressive signal amplification from the receptor, conducive to cell survival, proliferation, or metastasis. Here we report on studies of the i...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2010
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3075438/ https://ncbi.nlm.nih.gov/pubmed/20589763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22754 |
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