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Targeting GSK-3 family members in the heart: A very sharp double-edged sword

The GSK-3 family of serine/threonine kinases, which is comprised of two isoforms (α and β), was initially identified as a negative regulator of glycogen synthase, the rate limiting enzyme of glycogen synthesis [1, 2]. In the 30 years since its initial discovery, the family has been reported to regul...

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Autors principals: Cheng, Hui, Woodgett, James, Maamari, Mia, Force, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075376/
https://ncbi.nlm.nih.gov/pubmed/21163265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.11.020
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