The multiple functions of cytochrome c and their regulation in life and death decisions of the mammalian cell: from respiration to apoptosis

Cytochrome c (Cytc) is essential in mitochondrial electron transport and intrinsic type II apoptosis. Mammalian Cytc also scavenges reactive oxygen species (ROS) under healthy conditions, produces ROS with the co-factor p66(Shc), and oxidizes cardiolipin during apoptosis. The recent finding that Cyt...

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Main Authors: Hüttemann, Maik, Pecina, Petr, Rainbolt, Matthew, Sanderson, Thomas H., Kagan, Valerian E., Samavati, Lobelia, Doan, Jeffrey W., Lee, Icksoo
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075374/
https://ncbi.nlm.nih.gov/pubmed/21296189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2011.01.010
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