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Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine

Recurring waves of peri-infarct depolarizations (PIDs) propagate across gray matter in the hours and days following stroke, expanding the primary site of injury. Ischemic depolarization (termed anoxic depolarization or AD in live brain slices) is PID-like but immediately arises in the more metabolic...

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Bibliografiske detaljer
Main Authors: Douglas, Heather A., Callaway, Jennifer K., Sword, Jeremy, Kirov, Sergei A., Andrew, R. David
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075305/
https://ncbi.nlm.nih.gov/pubmed/21273307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00817.2010
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