Single Cell Genome Amplification Accelerates Identification of the Apratoxin Biosynthetic Pathway from a Complex Microbial Assemblage

Filamentous marine cyanobacteria are extraordinarily rich sources of structurally novel, biomedically relevant natural products. To understand their biosynthetic origins as well as produce increased supplies and analog molecules, access to the clustered biosynthetic genes that encode for the assembl...

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Detalhes bibliográficos
Main Authors: Grindberg, Rashel V., Ishoey, Thomas, Brinza, Dumitru, Esquenazi, Eduardo, Coates, R. Cameron, Liu, Wei-ting, Gerwick, Lena, Dorrestein, Pieter C., Pevzner, Pavel, Lasken, Roger, Gerwick, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075265/
https://ncbi.nlm.nih.gov/pubmed/21533272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018565
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