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Propionibacterium acnes CAMP Factor and Host Acid Sphingomyelinase Contribute to Bacterial Virulence: Potential Targets for Inflammatory Acne Treatment

BACKGROUND: In the progression of acne vulgaris, the disruption of follicular epithelia by an over-growth of Propionibacterium acnes (P. acnes) permits the bacteria to spread and become in contact with various skin and immune cells. METHODOLOGY/PRINCIPAL FINDINGS: We have demonstrated in the present...

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Detalhes bibliográficos
Main Authors: Nakatsuji, Teruaki, Tang, De-chu C., Zhang, Liangfang, Gallo, Richard L., Huang, Chun-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075254/
https://ncbi.nlm.nih.gov/pubmed/21533261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014797
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