Dynamic Analysis of Stochastic Transcription Cycles

In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses. To investigate the origins of this behavior and to understand its functional relevance, we quantitatively analyzed this variability using ne...

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Hauptverfasser: Harper, Claire V., Finkenstädt, Bärbel, Woodcock, Dan J., Friedrichsen, Sönke, Semprini, Sabrina, Ashall, Louise, Spiller, David G., Mullins, John J., Rand, David A., Davis, Julian R. E., White, Michael R. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075210/
https://ncbi.nlm.nih.gov/pubmed/21532732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000607
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