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Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology

Mitochondrial dysfunctions contribute to neurodegeneration, the locations of which vary among neurodegenerative diseases. To begin to understand what mechanisms may underlie higher vulnerability of the spinal cord motor neurons in amyotrophic lateral sclerosis, compared with brain mitochondria, we s...

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Detalhes bibliográficos
Main Authors: Panov, Alexander V., Kubalik, Nataliya, Zinchenko, Natalia, Ridings, Daisy M., Radoff, David A., Hemendinger, Richelle, Brooks, Benjamin R., Bonkovsky, Herbert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075084/
https://ncbi.nlm.nih.gov/pubmed/21248309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00528.2010
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