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Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology

Mitochondrial dysfunctions contribute to neurodegeneration, the locations of which vary among neurodegenerative diseases. To begin to understand what mechanisms may underlie higher vulnerability of the spinal cord motor neurons in amyotrophic lateral sclerosis, compared with brain mitochondria, we s...

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Bibliografski detalji
Glavni autori: Panov, Alexander V., Kubalik, Nataliya, Zinchenko, Natalia, Ridings, Daisy M., Radoff, David A., Hemendinger, Richelle, Brooks, Benjamin R., Bonkovsky, Herbert L.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3075084/
https://ncbi.nlm.nih.gov/pubmed/21248309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00528.2010
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