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Stimulation of A(2a) adenosine receptor abolishes the inhibitory effect of arachidonic acid on the basolateral 50-pS K channel in the thick ascending limb

The basolateral 50-pS K channels are stimulated by a cAMP-dependent pathway and inhibited by cytochrome P-450-omega-hydroxylase-dependent metabolism of arachidonic acid (AA) in the rat thick ascending limb (TAL). We now used the patch-clamp technique to examine whether stimulation of adenosine A(2a)...

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Detalhes bibliográficos
Main Authors: Wang, Mingxiao, Sui, Hongyu, Li, Wennan, Wang, Jing, Liu, Yujie, Gu, Li, Wang, Wen-Hui, Gu, Ruimin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074993/
https://ncbi.nlm.nih.gov/pubmed/21209003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00617.2010
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