Tip30 Deletion in MMTV-Neu Mice Leads to Enhanced EGFR Signaling and Development of Estrogen Receptor-Positive and Progesterone Receptor-Negative Mammary Tumors

Estrogen receptor-positive and progesterone receptor-negative (ER+/PR−) breast cancers account for 15–25% of all human breast cancers and display more aggressive malignant characteristics compared to ER+/PR+ cancers. However, the molecular mechanism underlying development of ER+/PR− breast cancers s...

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Autori principali: Zhang, Chengliang, Mori, Mikito, Gao, Shenglan, Li, Aimin, Hoshino, Isamu, Aupperlee, Mark D., Haslam, Sandra Z., Xiao, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074979/
https://ncbi.nlm.nih.gov/pubmed/21159643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3057
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