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Chronic Human Infection with Trypanosoma cruzi Drives CD4(+) T Cells to Immune Senescence

Previously we found that the frequency of IFN-γ-producing CD8(+) T cells specific for Trypanosoma cruzi inversely correlates with disease severity in chronic human Chagas disease along with low levels of IL-2-secreting CD8(+) T cells in all clinical stages. This impairment of the parasite-specific T...

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Autors principals: Albareda, María Cecilia, Olivera, Gabriela Carina, Laucella, Susana A., Alvarez, María Gabriela, Fernandez, Esteban Rodrigo, Lococo, Bruno, Viotti, Rodolfo, Tarleton, Rick L., Postan, Miriam
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074976/
https://ncbi.nlm.nih.gov/pubmed/19692645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900852
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