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Drug-induced cure drives conversion to a stable and protective CD8(+) T central memory response in chronic Chagas disease
In this study, we document the development of stable, antigen-independent CD8(+) T cell memory after drug-induced cure of a chronic infection. By establishing a system for drug cure of chronic Trypanosoma cruzi infection, we present the first extensively documented case of total parasite clearance a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074975/ https://ncbi.nlm.nih.gov/pubmed/18425131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1744 |
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