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A Computational Evaluation of the Mechanism of Penicillin-Binding Protein Catalyzed Cross-linking of the Bacterial Cell Wall

Penicillin-binding protein 1b (PBP 1b) of the Gram-positive bacterium Streptococcus pneumoniae catalyzes the cross-linking of adjacent peptidoglycan strands, as a critical event in the biosynthesis of its cell wall. This enzyme is representative of the biosynthetic PBP structures of the β-lactam-rec...

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Autors principals: Shi, Qicun, Meroueh, Samy O., Fisher, Jed F., Mobashery, Shahriar
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074971/
https://ncbi.nlm.nih.gov/pubmed/21417389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1074739
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