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Platelet-activating factor and metastasis: calcium-independent phospholipase A(2)β deficiency protects against breast cancer metastasis to the lung

We determined the contribution of calcium-independent phospholipase A(2)β (iPLA(2)β) to lung metastasis development following breast cancer injection into wild-type (WT) and iPLA(2)β-knockout (iPLA(2)β-KO) mice. WT and iPLA(2)β-KO mice were injected in the mammary pad with 200,000 E0771 breast cance...

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Main Authors: McHowat, Jane, Gullickson, Gail, Hoover, Richard G., Sharma, Janhavi, Turk, John, Kornbluth, Jacki
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074634/
https://ncbi.nlm.nih.gov/pubmed/21228317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00502.2010
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