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MicroRNAs are Transported in Plasma and Delivered to Recipient Cells by High-Density Lipoproteins

Circulating microRNAs (miRNA) are relatively stable in plasma and are a new class of disease biomarkers. Here we present evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional targeting capabilities. Cellular export of miRNAs to...

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Detalhes bibliográficos
Main Authors: Vickers, Kasey C., Palmisano, Brian T., Shoucri, Bassem M., Shamburek, Robert D., Remaley, Alan T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074610/
https://ncbi.nlm.nih.gov/pubmed/21423178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2210
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