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The BRAF(V600E) mutation: what is it really orchestrating in thyroid cancer?
BRAF(V600E) is a constitutively active onco-kinase and is the most common genetic alteration in papillary thyroid carcinoma (PTC), and in anaplastic thyroid carcinoma as well, albeit at a lower frequency. The BRAF(V600E) mutation in some studies has been significantly associated with extra-thyroidal...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074562/ https://ncbi.nlm.nih.gov/pubmed/21321384 |
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