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Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells
Clear cell renal cell carcinoma (CCRCC) evolves due to mutations in the von Hippel-Lindau (VHL) tumor suppressor gene. Although the loss of VHL enables the survival and proliferation of CCRCC cells, it is also expected to introduce vulnerabilities which may be exploited for therapeutics discovery. T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074515/ https://ncbi.nlm.nih.gov/pubmed/21199801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0757 |
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