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Characterization of Aquifex aeolicus ribonuclease III and the reactivity epitopes of its pre-ribosomal RNA substrates

Ribonuclease III cleaves double-stranded (ds) structures in bacterial RNAs and participates in diverse RNA maturation and decay pathways. Essential insight on the RNase III mechanism of dsRNA cleavage has been provided by crystallographic studies of the enzyme from the hyperthermophilic bacterium, A...

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Bibliographic Details
Main Authors: Shi, Zhongjie, Nicholson, Rhonda H., Jaggi, Ritu, Nicholson, Allen W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074117/
https://ncbi.nlm.nih.gov/pubmed/21138964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1030
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