Single strand targeted triplex formation: targeting purine-pyrimidine mixed sequences using abasic linkers.
Foldback triplex-forming oligonucleotides (FTFOs) that contain an abasic linker, [2-(4-aminobutyr-1-yl)-1,3-propanediol] (APD linker), in the Hoogsteen domain against pyrimidine bases of a C:G and a T:A base pair were studied for their relative stability and sequence specificity of triplex formation...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
1995
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| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307411/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7501477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.21.4510 |
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