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When is an optimization not an optimization? Evaluation of clinical implications of information content (signal-to-noise ratio) in optimization of cardiac resynchronization therapy, and how to measure and maximize it

Impact of variability in the measured parameter is rarely considered in designing clinical protocols for optimization of atrioventricular (AV) or interventricular (VV) delay of cardiac resynchronization therapy (CRT). In this article, we approach this question quantitatively using mathematical simul...

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Bibliographic Details
Main Authors: Pabari, Punam A., Willson, Keith, Stegemann, Berthold, van Geldorp, Irene E., Kyriacou, Andreas, Moraldo, Michela, Mayet, Jamil, Hughes, Alun D., Francis, Darrel P.
Format: Artigo
Language:Inglês
Published: Springer US 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074062/
https://ncbi.nlm.nih.gov/pubmed/21110226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10741-010-9203-5
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