CD8(+) T Cells and IFN-γ Mediate the Time-Dependent Accumulation of Infected Red Blood Cells in Deep Organs during Experimental Cerebral Malaria

BACKGROUND: Infection with Plasmodium berghei ANKA (PbA) in susceptible mice induces a syndrome called experimental cerebral malaria (ECM) with severe pathologies occurring in various mouse organs. Immune mediators such as T cells or cytokines have been implicated in the pathogenesis of ECM. Red blo...

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Bibliografiske detaljer
Main Authors: Claser, Carla, Malleret, Benoît, Gun, Sin Yee, Wong, Alicia Yoke Wei, Chang, Zi Wei, Teo, Pearline, See, Peter Chi Ee, Howland, Shanshan Wu, Ginhoux, Florent, Rénia, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073989/
https://ncbi.nlm.nih.gov/pubmed/21494565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018720
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