Rgs2 Mediates Pro-Angiogenic Function of Myeloid Derived Suppressor Cells in the Tumor Microenvironment via Upregulation of MCP-1

BACKGROUND: Tumor growth is intimately linked with stromal interactions. Myeloid derived suppressor cells (MDSCs) are dramatically elevated in cancer patients and tumor bearing mice. MDSCs modulate the tumor microenvironment through attenuating host immune response and increasing vascularization. ME...

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Detalhes bibliográficos
Main Authors: Boelte, Kimberly C., Gordy, Laura E., Joyce, Sebastian, Thompson, Mary Ann, Yang, Li, Lin, P. Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073977/
https://ncbi.nlm.nih.gov/pubmed/21494556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018534
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