Replicase-based plasmid DNA shows anti-tumor activity

BACKGROUND: Double stranded RNA (dsRNA) has multiple anti-tumor mechanisms. Over the past several decades, there have been numerous attempts to utilize synthetic dsRNA to control tumor growth in animal models and clinical trials. Recently, it became clear that intracellular dsRNA is more effective t...

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Bibliographic Details
Main Authors: Rodriguez, B Leticia, Yu, Zhen, Chung, Woon-Gye, Weiss, Richard, Cui, Zhengrong
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073940/
https://ncbi.nlm.nih.gov/pubmed/21443770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-110
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