Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites

BACKGROUND: The genome of a number of species of malaria parasites (Plasmodium spp.) has been sequenced in the hope of identifying new drug and vaccine targets. However, almost one-half of predicted Plasmodium genes are annotated as hypothetical and are difficult to analyse in bulk due to the ineffi...

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Main Authors: Fonager, Jannik, Franke-Fayard, Blandine MD, Adams, John H, Ramesar, Jai, Klop, Onny, Khan, Shahid M, Janse, Chris J, Waters, Andrew P
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073922/
https://ncbi.nlm.nih.gov/pubmed/21418605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-155
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