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Requirement for Plk2 in orchestrated Ras and Rap signaling, homeostatic structural plasticity, and memory
Ras and Rap small GTPases are important for synaptic plasticity and memory. However, their roles in homeostatic plasticity are unknown. Here, we report that polo-like kinase 2 (Plk2), a homeostatic suppressor of overexcitation, governs the activity of Ras and Rap via coordination of their regulatory...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073828/ https://ncbi.nlm.nih.gov/pubmed/21382555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.02.004 |
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