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1α,25-Dihydroxyvitamin D(3)-3β-bromoacetate, a potential cancer therapeutic agent: synthesis and molecular mechanism of action
Synthesis of 1α,25-dihydroxyvitamin D(3)-3β-bromoacetate (1,25(OH)(2)D(3)-3-BE), a potential anti-cancer agent is presented. We also report that mechanism of action of 1,25(OH)(2)D(3)-3-BE may involve reduction of its catabolism, as evidenced by the reduced and delayed expression of 1α,25-dihydroxyv...
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Päätekijät: | , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
2011
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073821/ https://ncbi.nlm.nih.gov/pubmed/21392983 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.02.025 |
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