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SYSTEMIC BUT NOT CENTRAL NERVOUS SYSTEM NITRIC OXIDE SYNTHASE INHIBITION EXACERBATES THE HYPERTENSIVE EFFECTS OF CHRONIC MELANOCORTIN-3/4 RECEPTOR ACTIVATION
We examined whether systemic or central nervous system (CNS) inhibition of nitric oxide (NO) synthase exacerbates the cardiovascular responses of chronic CNS melanocortin 3/4 receptor (MC3/4R) activation. Sprague-Dawley rats implanted with telemetry probes, venous catheters and intracerebroventricul...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3073740/ https://ncbi.nlm.nih.gov/pubmed/21263126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.163931 |
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