The Effects of Metformin with Lifestyle Therapy in Polycystic Ovary Syndrome: A Randomized Double Blind Study

OBJECTIVE: To determine if the combination of lifestyle(caloric restriction and exercise) and metformin(MET) would be superior to placebo and lifestyle(PBO) in improving PCOS phenotype. DESIGN: Double-blind randomized 6 month trial of MET vs PBO SETTING: Two academic medical centers PATIENTS: 114 su...

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Bibliographic Details
Main Authors: Ladson, Gwinnett, Dodson, William C., Sweet, Stephanie D., Archibong, Anthony E., Kunselman, Allen R., Demers, Laurence M, Williams, Nancy I, Coney, Ponjola, Legro, Richard S.
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073705/
https://ncbi.nlm.nih.gov/pubmed/21193187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2010.12.002
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