Dynamic Up-regulation of Prodynorphin Transcription in Temporal Lobe Epilepsy

Dynorphin neuropeptides are believed to act as endogenous anticonvulsants, though direct evidence for such a role in humans is sparse. We now report pronounced increases of prodynorphin mRNA expression in the dentate gyrus of patients with temporal lobe epilepsy in comparison to controls. We detecte...

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Main Authors: Pirker, Susanne, Gasser, Elisabeth, Czech, Thomas, Baumgartner, Christoph, Schuh, Elisabeth, Feucht, Martha, Novak, Klaus, Zimprich, Fritz, Sperk, Günther
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073604/
https://ncbi.nlm.nih.gov/pubmed/19437412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20633
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