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Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination

A hybrid protein structure determination approach combining sparse Electron Paramagnetic Resonance (EPR) distance restraints and Rosetta de novo protein folding has been previously demonstrated to yield high quality models (Alexander et al., 2008). However, widespread application of this methodology...

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Bibliografske podrobnosti
Main Authors: Kazmier, Kelli, Alexander, Nathan S., Meiler, Jens, Mchaourab, Hassane S.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073550/
https://ncbi.nlm.nih.gov/pubmed/21074624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.11.003
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