Fluorinated N,N-Dialkylaminostilbenes for Wnt Pathway Inhibition and Colon Cancer Repression

Colorectal cancer (CRC) is the second leading cause of cancer-related mortality in the United States. CRC is initiated by mutations of the tumor suppressor gene, adenomatous polyposis coli (APC) or β-catenin gene. These mutations stabilize β-catenin and constitutively activate Wnt/β-catenin target g...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Wen, Sviripa, Vitaliy, Kril, Liliia M., Chen, Xi, Yu, Tianxin, Shi, Jiandang, Rychahou, Piotr, Evers, B. Mark, Watt, David S., Liu, Chunming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073490/
https://ncbi.nlm.nih.gov/pubmed/21291235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm101248v
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